Coronin proteins are expressed in a large number of eukaryotic organisms from yeast to man.
Although Coronin is present almost all eukaryotic organisms and have different functions, but everywhere these proteins have been shown to bind F-actin and localize in the dynamic F-actin rich area of cells. Recent study shows that coronin prefers ATP/ADP-Pi containing F-actin over ADP containing F-actin, which might explain their unique cellular localization.
Coronin is an actin binding protein which also interacts with microtubules and in some cell types it is associated with phagocytosis.
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